Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV2) / (Record no. 1803)

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control field 20201123132702.0
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Title Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV2) /
Statement of responsibility, etc. Ruiyun Li [and six others]
520 3# - SUMMARY, ETC.
Summary, etc. Estimation of the prevalence and contagiousness of undocumented novel coronavirus [severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2)] infections is critical for understanding the overall prevalence and pandemic potential of this disease. Here, we use observations of reported infection within China, in conjunction with mobility data, a networked dynamic metapopulation model, and Bayesian inference, to infer critical epidemiological characteristics associated with SARS-CoV-2, including the fraction of undocumented infections and their contagiousness. We estimate that 86% of all infections were undocumented [95% credible interval (CI): 82-90%] before the 23 January 2020 travel restrictions. The transmission rate of undocumented infections per person was 55% the transmission rate of documented infections (95% CI: 46-62%), yet, because of their greater numbers, undocumented infections were the source of 79% of the documented cases. These findings explain the rapid geographic spread of SARS-CoV-2 and indicate that containment of this virus will be particularly challenging.
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Linking entry complexity note In: Science. 2020 vol.368 (6490) page: 489–493.<br/>Published online 2020 Mar 16. doi: 10.1126/science.abb3221
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Bayes Theorem
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Betacoronavirus
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Coronavirus Infections
General subdivision diagnosis
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Coronavirus Infections
General subdivision transmission
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Epidemiological Monitoring
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Topical term or geographic name entry element Travel
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Uncontrolled term COVID-19
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Personal name Li, Ruiyun
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Personal name Pei, Sen
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Personal name Chen, Bin
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Song, Yimeng
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Zhang, Tao
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Yang, Wan
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Shaman, Jeffrey
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Uniform Resource Identifier <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164387/">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164387/</a>
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Koha item type COVID 19 Resource
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-- 1803
-- 1803
Holdings
Withdrawn status Lost status Damaged status Not for loan Home library Current library Shelving location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
        DOH Central Library DOH Central Library Electronic Resource Section 11/23/2020   COVID-19-000066 D0001C000066 11/23/2020 11/23/2020 COVID 19 Resource