Emerging lethal infectious bronchitis coronavirus variants with multiorgan tropism / (Record no. 1807)

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fixed length control field 02120nam a22002897a 4500
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control field DOH
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control field 20201123135418.0
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245 00 - TITLE STATEMENT
Title Emerging lethal infectious bronchitis coronavirus variants with multiorgan tropism /
Statement of responsibility, etc. Yao-Tsun Li [and six others]
520 ## - SUMMARY, ETC.
Summary, etc. Infectious bronchitis virus (IBV) causes respiratory diseases in chickens and poses an economic threat to the poultry industry worldwide. Despite vaccine use, there have been field outbreaks of IBV in Taiwan. This study aimed to characterize the emerging IBV variants circulating in Taiwan. The analysis of the structural protein genes showed that these variants emerged through frequent recombination events among Taiwan strains, China strains, Japan strains and vaccine strains. Cross-neutralization tests revealed that two of the variants exhibited novel serotypes. Clinicopathological assessment showed that two of the variants caused high fatality rates of 67% and 20% in one-day-old SPF chicks, and all the variants possessed multiorgan tropisms, including trachea, proventriculus and urogenital tissues. Furthermore, the commercial live-attenuated Mass-type vaccine conferred poor protection against these variants. This study identified novel genotypes, serotypes and pathotypes of emerging IBV variants circulating in Taiwan. There is an urgent need for effective countermeasures against these variant strains.
580 ## - LINKING ENTRY COMPLEXITY NOTE
Linking entry complexity note In: Transboundary Emerging Disease. 2020 Vol. 67 (2) pages:884-893. <br/>doi: 10.1111/tbed.13412. Epub 2019 Nov 20.
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Bronchitis
General subdivision virology
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Coronavirus Infections
General subdivision epidemiology
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Disease Outbreaks
General subdivision veterinary
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Poultry Diseases
General subdivision epidemiology
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Viral Tropism
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Li, Yao‐Tsun
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Chen, Ting‐Chih
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Lin, Shu‐Yi
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Mase, Masaji
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Murakami, Shin
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Horimoto, Taisuke
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Chen, Hui‐Wen
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://onlinelibrary.wiley.com/doi/full/10.1111/tbed.13412">https://onlinelibrary.wiley.com/doi/full/10.1111/tbed.13412</a>
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type COVID 19 Resource
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-- 1807
-- 1807
Holdings
Withdrawn status Lost status Damaged status Not for loan Home library Current library Shelving location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
        DOH Central Library DOH Central Library Electronic Resource Section 11/23/2020   COVID-19-000068 D0001C000068 11/23/2020 11/23/2020 COVID 19 Resource