Molecular characterization of hepatitis G virus (HGV) isolates from healthy adults and risk groups in the Philippines / (Record no. 2744)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 02026nam a22002057a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DOH |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20210206133601.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210206b ||||| |||| 00| 0 eng d |
| 245 00 - TITLE STATEMENT | |
| Title | Molecular characterization of hepatitis G virus (HGV) isolates from healthy adults and risk groups in the Philippines / |
| Remainder of title | Ja Ricaforte-Campos [and three others] |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Hepatitis G virus (HGV) infection has been detected in Filipinos through a prospective study of 1,088 blood samples. HGV RNA was found in sera of 6/516 (1.2 percent) healthy adults (volunteer blood donors), 11/138 (8.0 percent) chronic liver disease patients, 7/207 (3.4 percent) hemodialysis patients, and 14/227 (6.2 percent) multiply transfused patients using reversetranscription polymerase chain reaction (RT-PCR) with random hexamer primers and a set of PCR primers from the 5 untranslated region (5UTR) of the HGV genome. A total of 38/1,088 subjects were HGV RNA-positive<br/>The PCR products derived from the 5UTR of HGV RNA+ samples were sequenced to determine the genotypic variant of HGV in the Philippines. Pairwise alignment of sequences and phylogenetic tree construction revealed that among the five known HGV genotypic variants, the Philippine isolates are most closely related to the Asian type (III)<br/>Considering that HGV is a highly mutable organism, surveillance for new genotypes may be the only way to assess accurate asymptomatic infection rates. How much this virus evolves in the future may have an impact on its virulence, transmissibility and invasiveness. It is therefore important, from an evolutionary perspective, to continue and monitor evolution of HGV specifically with studies at the molecular level. (Author) |
| 580 ## - LINKING ENTRY COMPLEXITY NOTE | |
| Linking entry complexity note | In: Acta Medica Philippina, 2005 vol. 39 (1) pages: 13-21 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | GB virus C |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Hepatitis G |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ricaforte-Campos, Jane D. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Domingo, Ernesto O. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Libranda-Ramirez, Bernadette DL |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dalmacio, Leslie Mic, |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| 999 ## - | |
| -- | 2744 |
| -- | 2744 |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| National Library of Medicine | DOH Central Library | DOH Central Library | Electronic Resource Section | 02/06/2021 | J000003 | D0001J000003 | 02/06/2021 | 02/06/2021 | Journal Article |