Serological evidence of human infection with SARS-CoV-2 : a systematic review and meta-analysis (Record no. 3789)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02976nam a22003617a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DOH |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20210326113135.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210326b ||||| |||| 00| 0 eng d |
| 245 00 - TITLE STATEMENT | |
| Title | Serological evidence of human infection with SARS-CoV-2 : a systematic review and meta-analysis |
| Statement of responsibility, etc. | Xinhua Chen [and eleven others] |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Background: A rapidly increasing number of serological surveys for anti-SARS-CoV-2 antibodies have been reported worldwide. A synthesis of this large corpus of data is needed.<br/><br/>Purpose: To evaluate the quality of serological studies and provide a global picture of seroprevalence across demographic and occupational groups, and to provide guidance for conducting better serosurveys.<br/><br/>Data sources: PubMed, Embase, Web of Science, medRxiv, bioRxiv, SSRN and Wellcome were searched for English-language papers published from December 1, 2019 to August 28, 2020.<br/><br/>Study selection: Serological studies that evaluated seroprevalence of SARS-CoV-2 infections in humans.<br/><br/>Data extraction: Two investigators independently extracted data from included studies.<br/><br/>Data synthesis: Most of 178 serological studies, representing tests in >800,000 individuals, identified were of low quality. Close contacts and high-risk healthcare workers had higher seroprevalence of 22.9% (95% CI: 11.1-34.7%) and 14.9% (4.8-25.0%), compared to low-risk healthcare workers and general population of 5.5% (4.6-6.4%) and 6.3% (5.5-7.1%). Generally, young people (0-20 yrs) were less likely to be seropositive compared to the middle-aged (21-55 yrs) populations (RR, 0.8, 95% CI: 0.7-0.8). Seroprevalence correlated with clinical COVID-19 reports with 10 (range: 2 to 34) infections per confirmed COVID-19 case.<br/><br/>Limitations: Some heterogeneity cannot be well explained quantitatively.<br/><br/>Conclusions: The overall quality of seroprevalence studies examined was low. The relatively low seroprevalence among general populations suggest that in most settings, antibody-mediated herd immunity is far from being reached. Given that ratio of infections to confirmed cases is on the same order of magnitude across different locales, reported case numbers may help provide insights into the proportion of the population infected. |
| 580 ## - LINKING ENTRY COMPLEXITY NOTE | |
| Linking entry complexity note | medRxiv 2020 Sep 13;2020.09.11.20192773. <br/>doi: 10.1101/2020.09.11.20192773 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | COVID-19 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Serologic Tests |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Coronavirus Infections |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Systematic Review |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | SARS-CoV-2 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Corona Virus |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chen, Xinhua |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chen, Zhiyuan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Azman, Andrew S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Deng, Xiaowei |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chen, Xinghui |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lu, Wanying |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zhao, Zeyao |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yang, Juan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Viboud, Cecile |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ajelli, Marco |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Leung, Daniel T |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yu, Hongjie |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491537/">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491537/</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | COVID 19 Resource |
| 999 ## - | |
| -- | 3789 |
| -- | 3789 |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| National Library of Medicine | DOH Central Library | DOH Central Library | Electronic Resource Section | 03/26/2021 | COVID-19-000164 | D0001C000164 | 03/26/2021 | 03/26/2021 | COVID 19 Resource |