The effect of clotrimazole 1% solution (Canesten) on the rate of corneal epithelial wound healing in rabbit eyes / (Record no. 4735)

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fixed length control field 01604nam a22002177a 4500
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control field DOH
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control field 20210519131526.0
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245 04 - TITLE STATEMENT
Title The effect of clotrimazole 1% solution (Canesten) on the rate of corneal epithelial wound healing in rabbit eyes /
Statement of responsibility, etc. Ma. Dominga B. Padilla [and two others]
520 3# - SUMMARY, ETC.
Summary, etc. We tested the effect of commercially prepared Clotrimazole 1% solution on the rate of closure of a standard 7 mm diameter corneal epithelial defect over a period of seven days and compared this to Natamycin 5% Suspension, 1% Amphotericin B Solution and placebo. The rate of closure in the Clotrimazole treated eyes was slightly slower than that of Natamycin and saline treated groups but did not significantly differ by the end of the study. Rate of wound closure was significantly slower in the Amphotericin treated eyes as compared to the Clotrimazole and the other treatment groups throughout the entire duration of the study. These findings, along with its known effectively and wide availability should push us to explore the potential of commercially prepared Clotrimazole 1% Solution as a viable alternative in the management of fungal keratitis.
580 ## - LINKING ENTRY COMPLEXITY NOTE
Linking entry complexity note <br/>Makati Medical Center Proceedings, 1999 (13) pages 62-66
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Corneal Injuries
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Wound Healing
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Clotrimazole
General subdivision administration and dosage
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Antifungal Agents
General subdivision therapeutic use
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Padilla, Ma. Dominga B.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Javellana, Juan Antonio G.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Valero, Sherman O.
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
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Holdings
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    National Library of Medicine     DOH Central Library DOH Central Library Electronic Resource Section 05/19/2021   J000658 D0001J000658 05/19/2021 05/19/2021 Journal Article