Impact of enhanced infection control at 2 neonatal intensive care units in the Philippines / (Record no. 570)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03344nab a2200325 i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DOH |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20200922112829.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200520t ph |||p| |||| 00| 0|eng|d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | DOH |
| Transcribing agency | DOH |
| 245 00 - TITLE STATEMENT | |
| Title | Impact of enhanced infection control at 2 neonatal intensive care units in the Philippines / |
| Statement of responsibility, etc. | Christopher J. Gill [and seven others] |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Background. The growing burden of neonatal mortality associated with hospital-acquired neonatal sepsis in<br/>the developing world creates an urgent need for cost-effective infection-control measures in resource-limited<br/>settings.<br/>Methods. Using a before-and-after comparison design, we measured how rates of staff hand-hygiene compliance,<br/>colonization with drug-resistant pathogens (defined as ceftazidime- and/or gentamicin-resistant gram-negative<br/>bacilli and drug-resistant gram-positive cocci), bacteremia, and overall mortality changed after the introduction<br/>of a simplified package of infection-control measures at 2 neonatal intensive care units (NICUs) in Manila,<br/>The Philippines.<br/>Results. Of all 1827 neonates admitted to the NICU, 561 (30.7%) arrived from delivery already colonized with<br/>drug-resistant bacteria. Of the 1266 neonates who were not already colonized, 578 (45.6%) became newly colonized<br/>with drug-resistant bacteria. Of all 1827 neonates, 358 (19.6%) became bacteremic (78.2% were infected with<br/>gram-negative bacilli) and 615 (33.7%) died. Of 2903 identified drug-resistant colonizing bacteria, 85% were drug-resistant<br/>gram-negative bacilli (predominantly Klebsiella species, Pseudomonas species, and Acinetobacter species)<br/>and 14% were methicillin-resistant Staphylococcus aureus. Contrasting the control period with the intervention<br/>period at each NICU revealed that staff hand-hygiene compliance improved (NICU 1: relative risk, 1.3; 95%<br/>confidence interval 1.1–1.5; NICU 2: relative risk, 1.6; 95% confidence interval, 1.4–2.0) and that overall mortality<br/>decreased (NICU 1: relative risk, 0.5; 95% confidence interval, 0.4–0.6; NICU 2: relative risk, 0.8; 95% confidence<br/>interval, 0.7–0.9). However, rates of colonization with drug-resistant pathogens and of sepsis did not change<br/>significantly at either NICU.<br/>Discussion. Nosocomial transmission of drug-resistant pathogens was intense at these 2 NICUs in The Philippines;<br/>transmission involved mostly drug-resistant gram-negative bacilli. Infection-control interventions are feasible<br/>and are possibly effective in resource-limited hospital settings. |
| Uniform Resource Identifier | <a href="https://pubmed.ncbi.nlm.nih.gov/19025496/">https://pubmed.ncbi.nlm.nih.gov/19025496/</a> |
| 580 ## - LINKING ENTRY COMPLEXITY NOTE | |
| Linking entry complexity note | In: Clinical Infectious Disease, 2009 vol. 48 (1) pages 13-21<br/> |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Anti-Bacterial Agents |
| General subdivision | pharmacology |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Bacteria |
| General subdivision | isolation and purification |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Bacterial Infections |
| General subdivision | prevention and control |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cross Infection |
| General subdivision | prevention and control |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Infant, Newborn |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Sepsis |
| General subdivision | prevention and control |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Intensive Care Units, Neonatal |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gill, Christopher J. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mantaring, Jose B. V. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Macleod, William B. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mendoza, Myrna |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mendoza, Sookee |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Huskins, W. Charles |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Goldmann, Donald A. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hamer, Davidson H. |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866590/">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866590/</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| Source of classification or shelving scheme | Dewey Decimal Classification |
No items available.