02025nam a22002537a 4500 D0001C000055 DOH 20201121113552.0 201121b ||||| |||| 00| 0 eng d The effect of mask use on the spread of influenza during a pandemic / Nicole C. J. Brienen [and four others] Face masks have traditionally been used in general infection control, but their efficacy at the population level in preventing transmission of influenza viruses has not been studied in detail. Data from published clinical studies indicate that the infectivity of influenza A virus is probably very high, so that transmission of infection may involve low doses of virus. At low doses, the relation between dose and the probability of infection is approximately linear, so that the reduction in infection risk is proportional to the reduction in exposure due to particle retention of the mask. A population transmission model was set up to explore the impact of population-wide mask use, allowing estimation of the effects of mask efficacy and coverage (fraction of the population wearing masks) on the basic reproduction number and the infection attack rate. We conclude that population-wide use of face masks could make an important contribution in delaying an influenza pandemic. Mask use also reduces the reproduction number, possibly even to levels sufficient for containing an influenza outbreak. In: Risk Analysis 2010 vol. 30 (8) pages: 1210–1218. Published online 2010 May 20. doi: 10.1111/j.1539-6924.2010.01428.x Influenza, Human prevention and control Influenza, Human transmission Masks Pandemics prevention and control Brienen, Nicole C. J. Timen, Aura Wallinga, Jacco Van Steenbergen, Jim E. Teunis, Peter F. M. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169241/pdf/RISA-30-1210.pdf CV 1788 1788 0 0 0 0 DOHCL DOHCL ElectronicRes 2020-11-21 0 COVID-19-000055 D0001C000055 2020-11-21 00:00:00 2020-11-21 CV