Chiong, Mary Anne D. Salonga, Edsel Allan G. Cutiongco-de la Paz, Eva Maria C. text monographic eng

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We describe two Filipino patients with Trisomy 8 mosaicism syndrome. Both had global developmental delay, mental deficiency, facial dysmorphism, skeletal deformities and the characteristic deep plantar and palmar creases. Their phenotype and radiologic features were consistent with the previously reported cases. Hematologic malignancies have recently been found to be associated with this chromosomal abnormality, emphasizing the importance of monitoring for cancer risks. Mary Anne D. Chiong [and two others] in: Acta Medica Philippina, 2008 vol 42 (2) pages: 55-59 Trisomy Mosaicism Hematologic Neoplasms Deep Palmar and Plantar Creases Skeletal Abnormalities https://actamedicaphilippina.upm.edu.ph/index.php/acta/article/view/2428/1750 https://actamedicaphilippina.upm.edu.ph/index.php/acta/article/view/2428/1750 210219 20210219122009.0 D0001J000070