01320nam a22001817a 4500001001300000003000400013005001700017008004100034245016500075520062600240580006200866650003200928650001800960700002800978700002201006700002801028856008201056D0001J000086DOH20210219145721.0210219b           ||||| |||| 00| 0 eng d00aVertebral osteomyelitis with profound neurologic deficit : bsuccessful treatment with rhBMP-2 and titanium cage device /cJonathan N. Sembrano [and two others]3 aThe efficacy of bone morphogenetic proteins (BMP) in infection has not yet been established. Since fusion is a necessary aim in the treatment of vertebral osteomyelitis with spinal instability, BMP may be a helpful adjunct in the surgical treatment of these cases. We present a case of vertebral osteomyelitis associated with neurologic deficits, treated with decompression and fusion using recombinant human bone morphogenetic protein-2 (rhBMP-2) and titanium cage device. Eradication of infection, recovery of neurologic deficits, spinal stabilization and solid fusion were achieved and maintained at 5 years follow-up.  aIn: Acta Medica Philippina, 2012 vol 46 (2) pages:  69-73 2aBone Morphogenetic Proteins 2aOsteomyelitis1 aSembrano, Jonathan  N. 1 aYson, Sharon  C. 1 aPolly, David  W.  cJr.  uhttps://actamedicaphilippina.upm.edu.ph/index.php/acta/article/view/2179/1594