successful treatment with rhBMP-2 and titanium cage device Sembrano, Jonathan N. Yson, Sharon C. Polly, David W. Jr text monographic eng

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The efficacy of bone morphogenetic proteins (BMP) in infection has not yet been established. Since fusion is a necessary aim in the treatment of vertebral osteomyelitis with spinal instability, BMP may be a helpful adjunct in the surgical treatment of these cases. We present a case of vertebral osteomyelitis associated with neurologic deficits, treated with decompression and fusion using recombinant human bone morphogenetic protein-2 (rhBMP-2) and titanium cage device. Eradication of infection, recovery of neurologic deficits, spinal stabilization and solid fusion were achieved and maintained at 5 years follow-up. Jonathan N. Sembrano [and two others] In: Acta Medica Philippina, 2012 vol 46 (2) pages: 69-73 Bone Morphogenetic Proteins Osteomyelitis https://actamedicaphilippina.upm.edu.ph/index.php/acta/article/view/2179/1594 https://actamedicaphilippina.upm.edu.ph/index.php/acta/article/view/2179/1594 210219 20210219145721.0 D0001J000086