02723nam a22004577a 4500 D0001J000162 DOH 20210312161126.0 210312b ||||| |||| 00| 0 eng d Serum gamma-glutamyltransferase levels after an alcohol challenge in two groups of medical students with different average alcohol consumption / Leilani Lucille Pichay [twenty three others] OBJECTIVES: This study aimed to compare the serum GGT levels of alcohol drinkers and controls METHODOLOGY: Eighteen to 28 year old Filipino male medical students of the University of the Philippines College of Medicine were recruited to answer a self-administered questionnaire determining patterns of alcohol intake. The subjects were then classified as drinkers (drinks alcohol of 60-120 g ethanol) and controls (weekly consumption of not more than 0.57 g ethanol). Serum GGT levels were obtained at baseline, after 28 days of abstinence and after alcohol challenge RESULTS: The GGT levels of the two groups were similar at baseline. Analysis of variance revealed a possible interaction between the grouping and the period of observation. Using the 28 day abstinence values as baseline, there was a difference in the changes in the GGT levels between the two groups after alcohol challenge. The mean GGT value in the drinkers group increased by 3 U/L while the mean GGT value in the control group decreased by 1.6 U/L. This difference was statistically significant (p-value=0.0023) CONCLUSION: These findings showed that the alcohol challenge test can be a diagnostic tool in determining individuals who have regularly ingested alcohol within this studys specified range. Acta Medica Philippina,1997 33 ( 3 ) pages 103-110 gamma-Glutamyltransferase Serum Alcohol Drinking Pichay, Leilani Lucille Tan, Jennifer Francisco, Ma. Jennina Palileo, Lia Aileen Tandoc, Neil Alvin Estrada, Dexter Francis Medina, Edgar Silva, Arvin Thomas Dimaialuan, Conrad Narsil Libames, Nikki Rose Strebel, Heinrik Martin Jude Zafra, Mario Adrian Domingo, Dewi Lim, Melody Severino, Oliver Gerald Valte, David Alonzo, Marian Lopez, Celeste Cheryll Ronque, Peter Paul Tecson, Ma. Pamela Feir, Sherwin Quijano, Dennis Tan, Chuck Lester Fontanilla, Regina JA 3476 3476 0 0 nlm 0 0 DOHCL DOHCL ElectronicRes 2021-03-12 0 J000162 D0001J000162 2021-03-12 00:00:00 2021-03-12 JA