01832nam a22002057a 4500 D0001J000560 DOH 20210428145349.0 210428b ||||| |||| 00| 0 eng d Metastatic mammary carcinoma in a mature singleton placenta / Francia Victoria A. De Los Reyes, Arlene L. Santos Introduction Placental metastasis from maternal malignancies is a rare occurrence with a significantly adverse prognosis on the mother with no known effect or established risk factors for the newborn. As such, characterization of these lesions is necessary to serve as a stepping stone for more exhaustive studies regarding this presentation. Case Summary This is a case of a metastatic breast carcinoma in a mature singleton placenta in a 39 year old woman diagnosed with invasive breast carcinoma of no special type/invasive ductal carcinoma, not otherwise specified, during the second trimester of pregnancy. Also discussed are the immunohistochemistry studies done to confirm the origin of the tumor. A comparison of the ER, PR, and HER2/neu receptor status between the primary lesion and the placental metastasis was also done. Conclusion Pregnancy-associated breast cancer is a lesion that carries adverse prognosis for the because of the delay in diagnosis attributable to confusion of symptomatology. The pertinent problem in pregnancy-associated breast cancer with placental metastasis is the deficiency of the placenta to induce tumor metastasis away from itself. UERM Health Science Journal, 2017 6 (1) pages 38-44 Neoplasm Metastasis Breast Neoplasms Placental Metastasis Metastatic Breast Carcinoma De Los Reyes, Francia Victoria A. Santos, Arlene L. JA 4300 4300 0 0 nlm 0 0 DOHCL DOHCL ElectronicRes 2021-04-28 0 J000560 D0001J000560 2021-04-28 00:00:00 2021-04-28 JA