02237nam a22003017a 4500999001300000001001300013003000400026005001700030008004100047040001300088245018800101520116600289580007101455650004001526650004301566650003201609650002801641650004801669653001601717700002601733700002401759700002501783700001701808700002401825700002101849856005801870942000701928 c686d686D0001E000029DOH20200806155502.0200521b ph ||||| |||| 00| 0 eng d aDOHcDOH00aCorrelates of gonococcal infection and of antimicrobial-resistant neisseria gonorrhoeae among females sex workers, Republic of the Philippines /cJeffrey D. Klausner [and five others]3 aFrom 1994 to 1997, the proportion of Neisseria gonorrhoeae highly resistant to ciprofloxacin (MIC >/=4 microg/mL) increased substantially among female sex workers (FSWs) in the Philippines. Among 1499 Filipina FSWs, we evaluated factors associated with gonococcal infection and with gonococcal antimicrobial resistance. By multivariate analysis, gonococcal infection was associated with sex with a new client, self-prescribed prophylactic antimicrobial use, work in a brothel, and inconsistent condom use and was negatively associated with registration status and vaginal hygiene practices. Factors associated with ciprofloxacin-resistant gonococci included: marital status, living alone, duration of sex work, and clinic site. Further, gonococci highly resistant to ciprofloxacin were isolated from 10 (11.5%) of 87 FSWs reporting self-prescribed antimicrobial use versus 44 (3.4%) of 1295 reporting no antimicrobial use (P<.001). Self-prescribed prophylactic antimicrobial use and inconsistent condom use could be important factors in the continued emergence of gonococcal antimicrobial resistance in the Philippines.uhttps://pubmed.ncbi.nlm.nih.gov/9952388/ aIn: Journal of Infectious Diseases, 1999 Vol. 179 (3) pages 729-33 2aAnti-Infective Agentsxpharmacology 2aAnti-Infective Agentsxtherapeutic use 2aCiprofloxacinxpharmacology 2aGonorrheaxdrug therapy 2aSexually Transmitted Diseasesxepidemiology aSex Workers1 aKlausner, Jeffrey D. 1 aAplasca, Mari-Rose 1 aMesola, Virginia P. 1 a Bolan, Gail1 aWhittington, W. L. 1 aHolmes, King K.  uhttps://academic.oup.com/jid/article/179/3/729/809506 cJA