Serum gamma-glutamyltransferase levels after an alcohol challenge in two groups of medical students with different average alcohol consumption / Leilani Lucille Pichay [twenty three others]

Contributor(s): Subject(s): Abstract: OBJECTIVES: This study aimed to compare the serum GGT levels of alcohol drinkers and controls METHODOLOGY: Eighteen to 28 year old Filipino male medical students of the University of the Philippines College of Medicine were recruited to answer a self-administered questionnaire determining patterns of alcohol intake. The subjects were then classified as drinkers (drinks alcohol of 60-120 g ethanol) and controls (weekly consumption of not more than 0.57 g ethanol). Serum GGT levels were obtained at baseline, after 28 days of abstinence and after alcohol challenge RESULTS: The GGT levels of the two groups were similar at baseline. Analysis of variance revealed a possible interaction between the grouping and the period of observation. Using the 28 day abstinence values as baseline, there was a difference in the changes in the GGT levels between the two groups after alcohol challenge. The mean GGT value in the drinkers group increased by 3 U/L while the mean GGT value in the control group decreased by 1.6 U/L. This difference was statistically significant (p-value=0.0023) CONCLUSION: These findings showed that the alcohol challenge test can be a diagnostic tool in determining individuals who have regularly ingested alcohol within this studys specified range.
Hello from Record Display Customizations!
Tags from this library: No tags from this library for this title. Log in to add tags.
    Average rating: 0.0 (0 votes)
Cover image Item type Current library Home library Collection Shelving location Call number Materials specified Vol info URL Copy number Status Notes Date due Barcode Item holds Item hold queue priority Course reserves
Journal Article DOH Central Library Electronic Resource Section J000162 (Browse shelf) Available D0001J000162

OBJECTIVES: This study aimed to compare the serum GGT levels of alcohol drinkers and controls METHODOLOGY: Eighteen to 28 year old Filipino male medical students of the University of the Philippines College of Medicine were recruited to answer a self-administered questionnaire determining patterns of alcohol intake. The subjects were then classified as drinkers (drinks alcohol of 60-120 g ethanol) and controls (weekly consumption of not more than 0.57 g ethanol). Serum GGT levels were obtained at baseline, after 28 days of abstinence and after alcohol challenge RESULTS: The GGT levels of the two groups were similar at baseline. Analysis of variance revealed a possible interaction between the grouping and the period of observation. Using the 28 day abstinence values as baseline, there was a difference in the changes in the GGT levels between the two groups after alcohol challenge. The mean GGT value in the drinkers group increased by 3 U/L while the mean GGT value in the control group decreased by 1.6 U/L. This difference was statistically significant (p-value=0.0023) CONCLUSION: These findings showed that the alcohol challenge test can be a diagnostic tool in determining individuals who have regularly ingested alcohol within this studys specified range.

Acta Medica Philippina,1997 33 ( 3 ) pages 103-110

There are no comments on this title.

to post a comment.