000			02903nam a22003497a 4500
999			_c225 _d225
001			C000008
003			DOH
005			20200806155447.0
008			200325b ph ||||| |||| 00| 0 eng d
040			_cDOH
245	0	2	_aA cluster randomised trial of cloth masks compared with medical masks in healthcare workers / _cC Raina Macintyre [and eight others]
260			_bBMJ Open, _c2015.
300			_a10 pages
336			_a[journal article]
504			_aIncludes bibliographic references.
520		3	_aABSTRACT Objective: The aim of this study was to compare the efficacy of cloth masks to medical masks in hospital healthcare workers (HCWs). The null hypothesis is that there is no difference between medical masks and cloth masks. Setting: 14 secondary-level/tertiary-level hospitals in Hanoi, Vietnam. Participants: 1607 hospital HCWs aged ≥18years working full-time in selected high-risk wards. Intervention: Hospital wards were randomised to: medical masks, cloth masks or a control group (usual practice, which included mask wearing). Participants used the mask on every shift for 4 consecutive weeks. Main outcome measure: Clinical respiratory illness (CRI), influenza-like illness (ILI) and laboratoryconfirmed respiratory virus infection. Results: The rates of all infection outcomes were highest in the cloth mask arm, with the rate of ILI statistically significantly higher in the cloth mask arm (relative risk (RR)=13.00, 95% CI 1.69 to 100.07) compared with the medical mask arm. Cloth masks also had significantly higher rates of ILI compared with the control arm. An analysis by mask use showed ILI (RR=6.64, 95% CI 1.45 to 28.65) and laboratoryconfirmed virus (RR=1.72, 95% CI 1.01 to 2.94) were significantly higher in the cloth masks group compared with the medical masks group. Penetration of cloth masks by particles was almost 97% and medical masks 44%. Conclusions: This study is the first RCT of cloth masks, and the results caution against the use of cloth masks. This is an important finding to inform occupational health and safety. Moisture retention, reuse of cloth masks and poor filtration may result in increased risk of infection. Further research is needed to inform the widespread use of cloth masks globally. However, as a precautionary measure, cloth masks should not be recommended for HCWs, particularly in high-risk situations, and guidelines need to be updated.
650		2	_aMasks
653			_aCloth Masks
653			_aMedical Masks
653			_aSurgical Masks
700	1		_aMacintyre, C Raina
700	1		_aSeale, Holly
700	1		_aTham, Chi Dung
700	1		_aNguyen, Tran Hien
700	1		_aPhan, Thi Nga
700	1		_aChugtai, Abrar Ahmad
700	1		_aRahman, Bayzidur
700	1		_aDwyer, Dominic E.
700	1		_aWang, Quanyi
856			_uhttps://bmjopen.bmj.com/content/bmjopen/5/4/e006577.full.pdf
942			_cCV _2nlm