000			01127nam a22001697a 4500
001			D0001J000255
003			DOH
005			20210320151642.0
008			210320b ||||| |||| 00| 0 eng d
100	1		_aYu, Marie Emmeline B.
245	0	0	_aParoxysmal nocturnal hemoglobinuria in a-17 year old (a case report) / _cMarie Emmeline B. Yu
520	3		_aA rare disease merits general attention if it is associated with extraordinary clinical manifestations, unusual laboratory findings, or an instructive molecular defect. Paroxysmal nocturnal hemoglobinuria has all three. Its clinical hallmark, tea-colored urine in arising from sleep, is graphic testimony to intravascular hemolysis during the night. Even more peculiar is the hemolysis that occurs after blood from a patient with PNH is mixed with acidified serum or ordinary table sugar. The molecular abnormality in PNH not only inform us about this unusual disease but also points to a genetic lesion of widespread interest.
580			_aCebu Doctors' Proceedings, 1995 11 (2) pages 73-77
650		2	_aHemoglobinuria, Paroxysmal
650		2	_aCase Reports
942			_cJA
999			_c3705 _d3705