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245 0 0 _aAttributes and predictors of long COVID /
_cCarole H. Sudre [and twenty three others]
520 3 _aReports of long-lasting coronavirus disease 2019 (COVID-19) symptoms, the so-called ‘long COVID’, are rising but little is known about prevalence, risk factors or whether it is possible to predict a protracted course early in the disease. We analyzed data from 4,182 incident cases of COVID-19 in which individuals self-reported their symptoms prospectively in the COVID Symptom Study app1. A total of 558 (13.3%) participants reported symptoms lasting ≥28 days, 189 (4.5%) for ≥8 weeks and 95 (2.3%) for ≥12 weeks. Long COVID was characterized by symptoms of fatigue, headache, dyspnea and anosmia and was more likely with increasing age and body mass index and female sex. Experiencing more than five symptoms during the first week of illness was associated with long COVID (odds ratio = 3.53 (2.76–4.50)). A simple model to distinguish between short COVID and long COVID at 7 days (total sample size, n = 2,149) showed an area under the curve of the receiver operating characteristic curve of 76%, with replication in an independent sample of 2,472 individuals who were positive for severe acute respiratory syndrome coronavirus 2. This model could be used to identify individuals at risk of long COVID for trials of prevention or treatment and to plan education and rehabilitation services.
580 _aNature Medicine (2021) doi.org/10.1038/s41591-021-01292-y
650 2 _aCOVID-19
650 2 _aLong Term Adverse Effects
700 1 _aSudre, Carole H.
700 1 _aMurray , Benjamin
700 1 _aVarsavsky, Thomas
700 1 _aGraham , Mark S.
700 1 _aPenfold, Rose S.
700 1 _aBowyer , Ruth C.
700 1 _aPujol, Joan Capdevila
700 1 _aKlaser, Kerstin
700 1 _a Antonelli, Michela
700 1 _aCanas, Liane S.
700 1 _aMolteni , Erika
700 1 _aModat, Marc
700 1 _aCardoso , M. Jorge
700 1 _aMay, Anna
700 1 _aGanesh , Sajaysurya
700 1 _aDavies , Richard
700 1 _aNguyen, Long H.
700 1 _aDrew , David A.
700 1 _aAstley, Christina M.
700 1 _aJoshi,  Amit D.
700 1 _aMerino , Jordi
700 1 _aTsereteli, Neli
700 1 _aFall, Tove
700 1 _aGomez , Maria F.
700 1 _aDuncan, Emma L.
700 1 _aMenni , Cristina
700 1 _aWilliams , Frances M. K.
700 1 _aFranks , Paul W.
700 1 _aChan , Andrew T.
700 1 _aWolf , Jonathan
700 1 _aOurselin , Sebastien
700 1 _aSpector , Tim
700 1 _aSteves , Claire J.
856 _uhttps://www.nature.com/articles/s41591-021-01292-y
942 _cCV
999 _c3794
_d3794