000			01832nam a22002057a 4500
001			D0001J000560
003			DOH
005			20210428145349.0
008			210428b ||||| |||| 00| 0 eng d
245	0	0	_aMetastatic mammary carcinoma in a mature singleton placenta / _cFrancia Victoria A. De Los Reyes, Arlene L. Santos
520	3		_aIntroduction Placental metastasis from maternal malignancies is a rare occurrence with a significantly adverse prognosis on the mother with no known effect or established risk factors for the newborn. As such, characterization of these lesions is necessary to serve as a stepping stone for more exhaustive studies regarding this presentation. Case Summary This is a case of a metastatic breast carcinoma in a mature singleton placenta in a 39 year old woman diagnosed with invasive breast carcinoma of no special type/invasive ductal carcinoma, not otherwise specified, during the second trimester of pregnancy. Also discussed are the immunohistochemistry studies done to confirm the origin of the tumor. A comparison of the ER, PR, and HER2/neu receptor status between the primary lesion and the placental metastasis was also done. Conclusion Pregnancy-associated breast cancer is a lesion that carries adverse prognosis for the because of the delay in diagnosis attributable to confusion of symptomatology. The pertinent problem in pregnancy-associated breast cancer with placental metastasis is the deficiency of the placenta to induce tumor metastasis away from itself.
580			_a UERM Health Science Journal, 2017 6 (1) pages 38-44
650		2	_aNeoplasm Metastasis
650		2	_aBreast Neoplasms
653			_aPlacental Metastasis
653			_aMetastatic Breast Carcinoma
700	1		_aDe Los Reyes, Francia Victoria A.
700	1		_aSantos, Arlene L.
942			_cJA
999			_c4300 _d4300