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245	0	0	_aCholangiocarcinoma and gallbladder carcinoma _b: Comparison of risk factors / _cCynthia C. Pollisco, Benjamin G. Benitez Jr
520	3		_aA cross-sectional retrospective study comparing the clinical profile and risk factors of gallbladder carcinoma and Cholangiocarcinoma patients from three hospitals in Metro Manila was done. A total of 40 cases from Santo Tomas University Hospital (STUH), East Avenue Medical Center and Makati Medical Center from 1992 - 2001 were reviewed. Of the forty patients, 28 (70 percent) had gallbladder carcinoma and 12 (30%) had Cholangiocarcinoma. Gallbladder carcinoma patients were mostly females (71.4 percent) with a mean age of 60 +/- 15.7 and patients with cholangiocarcinomas were mostly males (67.7 percent) and were older with a mean age of 72.5 +/- 2.2. Nineteen (67.9 percent) of gallbladder cancers presented in an advanc^fl stage (stage IV), while patients with Cholangiocarcinoma presented in earlier stages (25 percent in stage 1, 33.3 percent in stage 3). Most patients with gallbladder carcinoma had gallbladder stone and cholecystitis (85.7 percent and 64 percent, respectively). However, these were not present among most patients with Cholangiocarcinoma. Family history of cancer and porcelain gallbladder were not seen in the majority of patients in both groups. There were not much difference in the presenting signs and symptoms among the two groups. Signs and symptoms were similar in both groups. Liver profile as well as tumor markers were not available for all patients. For those with data, the transaminases, alkaline phosphatase and total bilirubin were elevated in a majority of patients in both groups. Conclusion. Although both gallbladder and Cholangiocarcinoma are biliary tract neoplasms, the demographic characteristics and risk factors of the two are very different. (Author)
580			_a Makati Medical Center Proceedings, 2004 (18) pages 16-20
650		2	_aCholangiocarcinoma
650		2	_aRisk Factors
653			_aGallbladder Carcinoma
700	1		_aPollisco, Cynthia C.
700	1		_aBenitez, Benjamin G. Jr
942			_cJA
999			_c4665 _d4665