000			01604nam a22002177a 4500
001			D0001J000658
003			DOH
005			20210519131526.0
008			210519b ||||| |||| 00| 0 eng d
245	0	4	_aThe effect of clotrimazole 1% solution (Canesten) on the rate of corneal epithelial wound healing in rabbit eyes / _cMa. Dominga B. Padilla [and two others]
520	3		_aWe tested the effect of commercially prepared Clotrimazole 1% solution on the rate of closure of a standard 7 mm diameter corneal epithelial defect over a period of seven days and compared this to Natamycin 5% Suspension, 1% Amphotericin B Solution and placebo. The rate of closure in the Clotrimazole treated eyes was slightly slower than that of Natamycin and saline treated groups but did not significantly differ by the end of the study. Rate of wound closure was significantly slower in the Amphotericin treated eyes as compared to the Clotrimazole and the other treatment groups throughout the entire duration of the study. These findings, along with its known effectively and wide availability should push us to explore the potential of commercially prepared Clotrimazole 1% Solution as a viable alternative in the management of fungal keratitis.
580			_a Makati Medical Center Proceedings, 1999 (13) pages 62-66
650		2	_aCorneal Injuries
650		2	_aWound Healing
650		2	_aClotrimazole _xadministration and dosage
650		2	_aAntifungal Agents _xtherapeutic use
700	1		_aPadilla, Ma. Dominga B.
700	1		_aJavellana, Juan Antonio G.
700	1		_aValero, Sherman O.
942			_cJA
999			_c4735 _d4735